Pre-ruminant cattle: administration in milk/milk replacer.
Pigs: administration in drinking water.
Duration of treatment: 3-5 days.
Pre-ruminant cattle 1.25 – 2.5 ml of product/10 kg BW/day, equivalent to 17500 – 35000 IU of paromomycin per kg BW/day (i.e. approximately 25-50 mg paromomycin sulfate per kg BW/day).
Pigs: 1.25 – 2 ml of product/10 kg BW/day, equivalent to 17500 – 28000 IU of paromomycin per kg BW/day (i.e. approximately 25-40 mg paromomycin sulfate per kg BW/day).
For the administration through the drinking water the exact daily amount of product should be based on the number of the animals to be treated, and the recommended dose calculated according to the following formula:
ml product/kg BW/day x Mean bodyweight (kg) of animals to be treated
= ml product per litre drinking water/day/animal
Mean daily water consumption (litre) per animal
To ensure a correct dosage bodyweight should be determined as accurately as possible.
The uptake of medicated water depends on several factors including clinical conditions of the animals and the local conditions such as ambient temperature and humidity. In order to obtain the correct dosage, uptake of drinking water has to be monitored and the concentration of paromomycin has to be adjusted accordingly.
Medicated drinking water/milk/milk replacer and any stock solutions should be freshly prepared every 6 hours (in milk/milk replacer) or every 24 hours (in water).